I'm not going to get into the whole "uses more gas" discussion. Instead I'm gonna weigh in on the JetManiac 781 Big Bore with other than stock 38mm carbs.
After my JM781 showed up, I stole a set of Mikuni 44mm SBN carbs and Pro-Tec intake manifold off a 96 Blaster I had sitting around. Chris (JetManiac) provided me with the following carb settings :
Main Jet = 110 H
Pilot Jet = 125 L
Needle/Seat = 2.3
Spring = 95
Pilot screw = adj 3/4 turn out
Main Screw = adj 1.25 turn out
It was pretty blubbery on the low end, so I started adjusting the screws. I'm currently at 3/4 turn out on both Lows and Highs. Cleaned it up a bit, but still not good enough. I'm ordering a set of 122.5 and 120 Pilot jets to see if that helps to clean up the low end. I'll update this when they arrive, I have them installed and tested.
My setup is as follows:
Gas Octane = 93
Altitude = sea level
Motor type/setup = bb781 61x/62t, 185 psi, 38cc domes, b pipe w/ mod chamber, MSD enhancer, #ZERO lightened flywheel, Pro-Tec intake manifold and Mikuni 44mm SBN carbs