It took them several tries with several different medications to get mine down to a reasonable level , I am on like five different meds , the BP medicine is a three in one type medication , on top of that I have to take Eliquis and Amarodone , the Eliquis is of course blood thinner, the Amarodone is to keep my heart in rhythm, I asked them about getting off the Amarodone and it's no dice unless I want to have an Ablation procedure done, I don't so I will just keep taking the meds , high BP does run in my family.