I do not like these kind of general 'what's best?' threads without alot more specifics. I think you need to know much more specifics on motor, pipe, and usage to choose the 'best.' What's best totally depends on the details- what is best for the exact setup and which is most important- price, performance, ease of tuning, fuel economy/range.
For example, a 61x/61x 701 motor with a stock head, stock cdi, and stock cases with home cylinder porting from a template kit (that ports exhaust only) with a Coffman sizzler pipe in a SN for a guy on a budget, then the choice is a single oem or a/m 44.
At the other end, a 62t motor bored to 760, running high compression with race gas, total loss, PFP, pro case and cylinder porting in flatwater hull, then dual 46s would be a good choice.